Modulation of Vascular Function in Endothelial Dysfunction and Arterial Occlusion Debulking (MODEVA)

Project no.: PP22/186

Project description:

The total prevalence of lower limb peripheral arterial disease (PAL) is 10%. between adults over 55 years of age. The risk of death in patients with PAL is up to 3 times higher than in patients without PAL, even with optimal medication.
Currently, one of the treatments for PAL is endovascular intervention (EI): percutaneous transluminal angioplasty and stenting. EI success depends on the complexity of the damage (calcification, chronic long total occlusion). In such cases, medical devices are used to facilitate the placement of the conduction wire, or atherectomy devices. The costs of such interventions are high. Failure of EI in the thoracic occlusion of the song is treated by a bowel movement. This is a risky operation. So far, there is no consensus that intervention is best suited for treating PAL. The goal of the project is to create an economical, safe, non-destructive method of aterectomy with a targeted drug delivery function. This will be achieved with a special device that causes ultrasound vibration and during the cavitation process when distributing the drug at the site of the injury.

Project funding:

KTU R&D&I Fund

Period of project implementation: 2018-03-20 - 2018-12-31

Project partners: Lithuanian University of Health Sciences

Head:
Algimantas Bubulis

Duration:
2018 - 2018

Department:
Institute of Mechatronics, Laboratory of Biomechatronics